Volume 3, Issue 1 (2014)
WJPS 2014, 3(1): 29-34 |
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1- Faculty of Plastic and Reconstructive Surgery, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran , akhoondinasab@yahoo.com
2- Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
3- Medicine, Quran and Hadith Research Center, Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
2- Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
3- Medicine, Quran and Hadith Research Center, Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
Abstract: (9583 Views)
BACKGROUND
Wound healing is widely discussed in the medical literature. This study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model.
METHODS
Sixteen rats were randomly assigned to one of two groups, each group 8 rats. A deep second-degree burn on the lower back and 3rd degree burn on upper back of each rat were created with a standard burning procedure. Burns were dressed daily with aloe vera extract in group 2 and silver sulfadiazine in group 1. Response to treatment was assessed by digital photography during treatment until day 32. Histological parameters (PMN, epithelialization, fibrosis and angiogenesis) were assessed after biopsy of scar at the end of research.
RESULTS
Wound healing was more visible in aloe vera group. Also the speed of healing in aloe vera group was better than silver sulfadiazine group.
CONCLUSIONS
Based on our findings, aloe vera can be a therapy of choice for burn injuries.
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